B6;129S-Dnmt1{tm1Jae/J}

eagle-i ID

Resource Type

Properties

1. Resource Description

   This mouse is heterozygous for Dnmt1 mutation. It's cryopreserved at Jackson Lab. "Mice homozygous for this mutation die at mid-gestation. The embryos are stunted and show a delayed development. DNA from these mice shows a reduction in the level of m5C to about 1/3 that seen in cells from normal wild type siblings." (http://jaxmice.jax.org/strain/002123.html)

2. Additional Name

   DNA (Cytosine-5-)-Methyltransferase 1 knockout

3. Additional Name

   Dnmt1-KO

4. Contact

   Bacanamwo, Methode, Ph.D.

5. Genetic Alteration(s)

   Dnmt1

6. Inserted Gene Entrez ID

   1786

7. Location

   Methode Bacanamwo Laboratory