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Berkeley knockout model

eagle-i ID


Resource Type

  1. Mus musculus


  1. Resource Description
    Berkeley knockout model is a complete knockout of murine alpha and beta globins followed by insertion of a transgene containing human alpha, beta, A gamma, G gamma globins.
  2. Additional Name
    SCD transgenic mouse model
  3. Additional Name
    Transgenic Sickle cell mouse model
  4. Related Disease
    sickle cell anemia
  5. Parental Strain Name
    5 parental strains including: C57Bl/6, 129, FVB/N, DBA/2, and Black Swiss
  6. Genetic Alteration(s)
    Alpha globin knockout
  7. Genetic Alteration(s)
    Beta globin knockout
  8. Genetic Alteration(s)
    Homo sapiens G gamma globin
  9. Genetic Alteration(s)
    Homo sapiens alpha globin
  10. Genetic Alteration(s)
    Homo sapiens A gamma globin
  11. Genetic Alteration(s)
    Homo sapiens beta globin
  12. Location
    J. Hibbert Laboratory
Provenance Metadata About This Resource Record
  1. workflow state
  2. contributor
  3. created
  4. creator
    ppullen (Paula Pullen)
  5. modified
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016