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Berkeley knockout model
eagle-i ID
http://msm.eagle-i.net/i/0000012d-c842-2a6f-9b30-a5a880000000
Resource Type
Properties
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Resource Description
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Berkeley knockout model is a complete knockout of murine alpha and beta globins followed by insertion of a transgene containing human alpha, beta, A gamma, G gamma globins.
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Additional Name
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SCD transgenic mouse model
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Additional Name
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Transgenic Sickle cell mouse model
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Related Disease
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sickle cell anemia
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Parental Strain Name
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5 parental strains including: C57Bl/6, 129, FVB/N, DBA/2, and Black Swiss
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Genetic Alteration(s)
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Alpha globin knockout
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Genetic Alteration(s)
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Beta globin knockout
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Genetic Alteration(s)
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Homo sapiens G gamma globin
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Genetic Alteration(s)
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Homo sapiens alpha globin
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Genetic Alteration(s)
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Homo sapiens A gamma globin
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Genetic Alteration(s)
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Homo sapiens beta globin
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Location
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J. Hibbert Laboratory