eagle-i Morehouse School of MedicineMorehouse School of Medicine
See it in Search
This page is a preview of the following resource. Continue onto eagle-i search using the button on the right to see the full record.

Powell, Michael D., Ph.D.

eagle-i ID

http://msm.eagle-i.net/i/0000012e-2583-005c-9b30-a5a880000000

Resource Type

  1. Person

Properties

  1. Resource Description
    "Our lab is interested in the molecular pathogenesis of HIV/AIDS. Our current projects focus on the role that the viral protein Nef plays in AIDS pathogenesis. We have found that the Nef protein is secreted from infected cells in small membrane-bound packages called "exosomes." These exosomes can fuse with non-infected cells and cause a variety of effects, including programmed cell death. Nef exosomes are also present in the plasma of HIV infected individuals. In collaboration with Dr. Vincent Bond at Morehouse School of Medicine, we are exploring the possibility that Nef exosomes could represent a major source of the T cell depletion, a hallmark of HIV/AIDS. We are currently testing this hypothesis in non-human primates and strategies are currently being devised to develop therapeutic vaccines and anti-virals based on this model. Our lab also provides Luminex assays, mass spectrometry and Proteomics services for the school. Those interested in initiating a project with the Proteomics core should contact Dr. Powell."
  2. First Name
    Michael D.
  3. Last Name
    Powell
  4. Title
    Associate Professor, Department of Microbiology, Biochemistry & Immunology
  5. Website(s)
    http://www.msm.edu/academic/microbiology/faculty/Michael_Powell.aspx
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    wroth (William Roth)
  3. created
    2011-02-14T13:05:55.470-06:00
  4. creator
    ppullen (Paula Pullen)
  5. modified
    2014-04-28T10:35:29.391-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016