Human Genome CGH+SNP microarray

eagle-i ID

Resource Type

Properties

1. Resource Description

   The Agilent SurePrint G3 Human Comparative Genomic Hybridization (CGH) platform has been extended to include a set of Single Nucleotide Polymorphism (SNP) probes on the same microarray. This allows for the simultaneous, high-resolution detection of copy number and copy-neutral variations, without running two separate microarray experiments. The same straight-forward Agilent CGH workflow is used to prepare the samples for hybridization to the SurePrint G3 Human CGH+SNP microarrays. Restriction digestion of genomic DNA allows genotyping of SNPs located in the enzymes’ recognition sites. After labeling and hybridization, CGH+SNP microarray data are analyzed using novel algorithms contained within Agilent’s Genomic Workbench software.

2. Manufacturer

   Agilent Technologies

3. Website(s)

   http://www.genomics.agilent.com/CollectionOverview.aspx?PageType=Application&SubPageType=ApplicationOverview&PageID=2394

4. Related Technique

   Nucleic acid microarray assay

5. Related Technique

   Copy number variation profiling

6. Location

   Functional Genomics Core Laboratory